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Biotinylated Cynomolgus CD6 / TP120 Protein, Fc, Avitag™ (MALS verified)

CD6 (Cluster of Differentiation 6) is a transmembrane protein primarily expressed on T-lymphocytes and certain other immune cells. Structurally, it is characterized by three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule (ALCAM) . Functionally, CD6 is critical for the continuation of T cell activation and exhibits scavenger receptor activity. Aberrant CD6 function is associated with diseases such as Multiple Sclerosis. Its paralog is DMBT1.

Product Specifications

Background

CD6 (Cluster of Differentiation 6) is a transmembrane protein primarily expressed on T-lymphocytes and certain other immune cells. Structurally, it is characterized by three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule (ALCAM) . Functionally, CD6 is critical for the continuation of T cell activation and exhibits scavenger receptor activity. Aberrant CD6 function is associated with diseases such as Multiple Sclerosis. Its paralog is DMBT1.

Specifications

This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 69 kDa. The protein migrates as 90-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

His 18 - Leu 399

Target

CD6

Conjugation

Biotin-labeled

Tag

C-Fc & C-Avi

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Molecular Weight

69 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

25ug*1

Host or Source

HEK293

Species

Cynomolgus

Protein ID

XP_005577746.1

Preservative

Trehalose

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