Monoclonal Anti-NMTi Antibody, Rabbit IgG (M1E05)
NMTi, a new ADC payload toxin developed by Myricx Bio, inhibits NMT to disrupt mitochondrial function and induce endoplasmic reticulum stress, thereby killing cancer cells. Its simple structure facilitates synthesis. In preclinical studies, it exhibits efficacy and safety in solid tumors; NMTi-ADCs feature dual targeting and strong bystander activity, and outperform T-Dxd in some models.
Product Specifications
Background
NMTi, a new ADC payload toxin developed by Myricx Bio, inhibits NMT to disrupt mitochondrial function and induce endoplasmic reticulum stress, thereby killing cancer cells. Its simple structure facilitates synthesis. In preclinical studies, it exhibits efficacy and safety in solid tumors; NMTi-ADCs feature dual targeting and strong bystander activity, and outperform T-Dxd in some models.
Target
NMTi
Conjugation
Unconjugated
Tag
Rabbit IgG | Rabbit Kappa
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.
Format
Powder
Buffer
PBS, pH7.4
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Host or Source
HEK293
Species
Rabbit
Preservative
Trehalose
Curated Selection
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