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Human DRD2 Full Length Protein (VLP)

Dopamine receptor D2 (DRD2) is G protein-coupled receptor (GPCR) that belong to the D2-like dopamine receptor family, couple to Gi to reduce adenylyl cyclase. DRD2s are expressed in different neuronal cell types within the striatum, dopamine binding leads to the inhibition of dopaminergic synaptic transmission. Altered expression level and function of DRD2s are observed in Parkinson's disease, making DRD2 one of the most common therapeutic targets for Parkinson's disease. DRD2 agonists can reduce the side effects of L-DOPA and enhance the therapeutic effect.

Product Specifications

Background

Dopamine receptor D2 (DRD2) is G protein-coupled receptor (GPCR) that belong to the D2-like dopamine receptor family, couple to Gi to reduce adenylyl cyclase. DRD2s are expressed in different neuronal cell types within the striatum, dopamine binding leads to the inhibition of dopaminergic synaptic transmission. Altered expression level and function of DRD2s are observed in Parkinson's disease, making DRD2 one of the most common therapeutic targets for Parkinson's disease. DRD2 agonists can reduce the side effects of L-DOPA and enhance the therapeutic effect.

Specifications

This protein .

Expression Region

Met 1 - Cys 443

Target

DRD2

Conjugation

Unconjugated

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.

Endotoxin

1.0 EU per μg

Format

Liquid

Buffer

PBS, Arginine, pH7.4

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

P14416-1

Preservative

Trehalose

Frequently Asked Questions

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