Human DRD2 Full Length Protein (VLP)
Dopamine receptor D2 (DRD2) is G protein-coupled receptor (GPCR) that belong to the D2-like dopamine receptor family, couple to Gi to reduce adenylyl cyclase. DRD2s are expressed in different neuronal cell types within the striatum, dopamine binding leads to the inhibition of dopaminergic synaptic transmission. Altered expression level and function of DRD2s are observed in Parkinson's disease, making DRD2 one of the most common therapeutic targets for Parkinson's disease. DRD2 agonists can reduce the side effects of L-DOPA and enhance the therapeutic effect.
Product Specifications
Background
Specifications
This protein .
Expression Region
Met 1 - Cys 443
Target
DRD2
Conjugation
Unconjugated
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.
Endotoxin
1.0 EU per μg
Format
Liquid
Buffer
PBS, Arginine, pH7.4
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
20ug*1
Host or Source
HEK293
Species
Human
Protein ID
P14416-1
Preservative
Trehalose
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