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Monoclonal Anti-NMTi Antibody, Rabbit IgG (M1C07)

NMTi, a new ADC payload toxin developed by Myricx Bio, inhibits NMT to disrupt mitochondrial function and induce endoplasmic reticulum stress, thereby killing cancer cells. Its simple structure facilitates synthesis. In preclinical studies, it exhibits efficacy and safety in solid tumors; NMTi-ADCs feature dual targeting and strong bystander activity, and outperform T-Dxd in some models.

Product Specifications

Background

NMTi, a new ADC payload toxin developed by Myricx Bio, inhibits NMT to disrupt mitochondrial function and induce endoplasmic reticulum stress, thereby killing cancer cells. Its simple structure facilitates synthesis. In preclinical studies, it exhibits efficacy and safety in solid tumors; NMTi-ADCs feature dual targeting and strong bystander activity, and outperform T-Dxd in some models.

Target

NMTi

Conjugation

Unconjugated

Tag

Rabbit IgG | Rabbit Kappa

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.

Format

Powder

Buffer

PBS, pH7.4

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

500ug*2

Host or Source

HEK293

Species

Rabbit

Preservative

Trehalose

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