Biotinylated Mouse H-2Dd&B2M&HIV env (IGPGRAFYA) Complex Protein (Monomer, MALS verified)

HIV (human immunodeficiency virus) is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome) . It can be transmitted via the exchange of a variety of body fluids from infected people, such as blood, breast milk, semen and vaginal secretions, And from a mother to her child during pregnancy and delivery. This disease can be managed by treatment regimens composed of a combination of antiretroviral (ARV) drugs. The Mouse H-2Dd HIV env (IGPGRAFYA) complex protein is a complex of H-2Dd of the MHC Class I, B2M, and IGPGRAFYA peptide of the HIV.

Product Specifications

Background

Specifications

Biotinylated Mouse H-2Dd&B2M&HIV env (IGPGRAFYA) Complex Protein is produced by co-expression of H-2Dd and B2M loaded with HIV env peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 40.1 kDa and 17.4 kDa. The protein migrates as 43-45 kDa and 19 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Gly 25 - Thr 311 (H-2Dd) & Ile 21 - Met 119 (B2M) & IGPGRAFYA peptide

Target

H-2Dd & B2M & HIV env (IGPGRAFYA)

Conjugation

Biotin-labeled

Tag

C-10xHis & C-Avi

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.