PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein

Melanoma-associated antigen A10 (MAGE-A10) is a cancer/testis protein associated with many cancers. MAGE-A10 is overexpressed in cancer cells. The repression of MAGE-A10 expression increased cell-cell and cell matrix adhesion. The Human HLA-A*0201 MAGE-A10 (GLYDGMEHL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and GLYDGMEHL peptide of the MAGE-A10.

Product Specifications

Background

Specifications

PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein is assembled by biotinylated monomer (HLM-H82Ec) and PE-labeled streptavidin. Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Complex Protein is produced by co-expression of HLA and B2M loaded with MAGE-A10 peptide. Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) .

Expression Region

Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & GLYDGMEHL peptide

Target

HLA-A*0201 & B2M & MAGE-A10 (GLYDGMEHL)

Conjugation

PE Labeled

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.