APC-Labeled Mouse H-2Kd&B2M&RSV F glycoprotein (KYKNAVTEL) Tetramer Protein

Respiratory syncytial virus (RSV) is a major cause of respiratory disease in infants and the elderly. The two major glycoproteins on the surface of the RSV virion, the attachment glycoprotein (G) and the fusion glycoprotein (F), control the initial phases of infection. G targets the ciliated cells of the airways, and F causes the virion membrane to fuse with the target cell membrane. The F protein is the major target for antiviral drug development, and both G and F glycoproteins are the antigens targeted by neutralizing antibodies induced by infection.The Mouse H-2Kb&B2M&RSV F glycoprotein (KYKNAVTEL) Tetramer Protein is a complex of H-2Kb of the MHC Class I, B2M, and KYKNAVTEL peptide of the RSV F glycoprotein.

Product Specifications

Background

Specifications

APC-Labeled Mouse H-2Kd&B2M&RSV F glycoprotein (KYKNAVTEL) Tetramer Protein is assembled by biotinylated monomer and APC-labeled streptavidin. Biotinylated Mouse H-2Kd&B2M&RSV F glycoprotein (KYKNAVTEL) Complex Protein is produced by co-expression of H-2Kd and B2M loaded with RSV F glycoprotein peptide. Biotinylated Mouse H-2Kd&B2M&RSV F glycoprotein (KYKNAVTEL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) .

Expression Region

Gly 22 - Thr 305 (H-2Kd) & Ile 21 - Met 119 (B2M) & KYKNAVTEL peptide

Target

H-2Kd & B2M & RSV F glycoprotein (KYKNAVTEL)

Conjugation

APC Labeled

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.