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PE-Labeled Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein

The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Biotinylated Human HLA-A*0301 KRASG12V (VVGAVGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVGAVGVGK peptide of the KRASG12V.

Product Specifications

Background

The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Biotinylated Human HLA-A*0301 KRASG12V (VVGAVGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVGAVGVGK peptide of the KRASG12V.

Specifications

PE-Labeled Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein is assembled by biotinylated monomer (HLV-H82E9) and PE-labeled streptavidin. Biotinylated Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide. Biotinylated Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) .

Expression Region

Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGAVGVGK peptide

Target

HLA-A*0301 & B2M & KRASG12V (VVGAVGVGK)

Conjugation

PE Labeled

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Format

Powder

Buffer

PBS, 1% BSA, pH7.4

Molecular Weight

36.1 kDa and 11.7 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C, avoid light

Package Size

25ug*1

Host or Source

HEK293

Species

Human

Protein ID

P04439-1 (HLA-A*03:01) & P61769 (B2M) & VVGAVGVGK

Preservative

Trehalose

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