APC-Labeled Human HLA-A*02:01&B2M&MAGE-A2 (YLQLVFGIEV) Tetramer Protein

The MAGE-A2 antigen is a cancer-testis antigen and is expressed intracellularly in various solid tumor tissues, MAGE-A2 157-166 peptide (YLQLVFGIEV) is a cytotoxic T lymphocyte (CTL) epitope presented by HLA-A*0201. The Human HLA-A*0201 MAGE-A2 (YLQLVFGIEV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, andYLQLVFGIEV peptide of the MAGE-A2.

Product Specifications

Background

Specifications

APC-Labeled Human HLA-A*02:01&B2M&MAGE-A2 (YLQLVFGIEV) Tetramer Protein is assembled by biotinylated monomer (HLM-H82E6) and APC-labeled streptavidin. Biotinylated Human HLA-A*02:01&B2M&MAGE-A2 (YLQLVFGIEV) Complex Protein is produced by co-expression of HLA and B2M loaded with NY-ESO-1 peptide. Biotinylated Human HLA-A*02:01&B2M&MAGE-A2 (YLQLVFGIEV) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) .

Expression Region

Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & YLQLVFGIEV peptide

Target

HLA-A*0201 & B2M & MAGE-A2 (YLQLVFGIEV)

Conjugation

APC Labeled

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.