PE-Labeled Human HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Tetramer Protein

Cytomegalovirus (Cytomegalovirus) is a herpes viral DNA virus. Human cytomegalovirus (HCMV) can only infect humans and multiply in humans. The antibodies. After primary infection with CMV, the body can produce specific antibodies and killer T lymphocytes to activate NM cells. The antibody has limited CMV replication ability and has a certain resistance to reinfection of the same strain, but cannot resist the activation of antibody-dependent virus and the exogenous infection of other different strains of CMV. However, specific killer T lymphocytes and antibody-dependent cytotoxic cells can exert the greatest antiviral effect. The Human HLA-A*0201 CMV (NLVPMVATV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and NLVPMVATV peptide of the CMV.

Product Specifications

Background

Specifications

PE-Labeled Human HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Tetramer Protein is assembled by biotinylated monomer (HLC-H82E5) and PE-labeled streptavidin. Biotinylated Human HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Complex Protein is produced by co-expression of HLA and B2M loaded with CMV pp65 peptide. Biotinylated Human HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) .

Expression Region

Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & NLVPMVATV peptide

Target

HLA-A*0201 & B2M & CMV pp65 (NLVPMVATV)

Conjugation

PE Labeled

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.