PE-Labeled Human HLA-A*02:01&B2M&Survivin (TLPPAWQPFL) Tetramer Protein

Survivin, also known as BIRC5 and EPR-1, is a member of the inhibitor of apoptosis (IAP) family, which encodes negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but birc5 encodes proteins with only a single BIR domain. The Human HLA-A*0201 Survivin (TLPPAWQPFL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and TLPPAWQPFL peptide of the Survivin.

Product Specifications

Background

Specifications

PE-Labeled Human HLA-A*02:01&B2M&Survivin (TLPPAWQPFL) Tetramer Protein is assembled by biotinylated monomer (HLN-H82E5) and PE-labeled streptavidin. Biotinylated Human HLA-A*02:01&B2M&Survivin (TLPPAWQPFL) Complex Protein is produced by co-expression of HLA and B2M loaded with Survivin peptide. Biotinylated Human HLA-A*02:01&B2M&Survivin (TLPPAWQPFL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) .

Expression Region

Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & CLGGLLTMV peptide

Target

HLA-A*0201 & B2M & Survivin (TLPPAWQPFL)

Conjugation

PE Labeled

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.