PE-Labeled Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Tetramer Protein

The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Human HLA-A*0201 KRASG12V (KLVVVGAVGV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and KLVVVGAVGV peptide of the KRASG12V.

PE-Labeled Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Tetramer Protein is assembled by biotinylated monomer (HLV-H82E3) and PE-labeled streptavidin. Biotinylated Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide. Biotinylated Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) .

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.