Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein (MALS verified)
Wilms tumor gene 1 (WT1), is an attractive target antigen for leukemia and solid cancer. WT1-specific adoptive immunotherapy has developed for tumor treatment in recent years. WT1 has been proved wildly expressed in breast, colon and ovarian cancer. It participates in cell growth, differentiation and apoptosis regulation. The WT1127-134 (RMFPNAPYL) was shown to be recognized by HLA-A*0201 tumor-infiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCR-T studies. The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1.
Product Specifications
Background
Specifications
Expression Region
Gly 25 - Thr 305 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & RMFPNAPYL peptide
Target
HLA-A*02:01 & B2M & WT-1 (RMFPNAPYL)
Conjugation
Unconjugated
Tag
C-10xHis
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Molecular Weight
36.0 kDa and 13.8 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*1
Host or Source
HEK293
Species
Human
Protein ID
AAA59606.1 (HLA-A*02:01) & P61769 (B2M) & RMFPNAPYL
Preservative
Trehalose
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