Anti-Thyroid Hormone Receptor, α1/α2-Isotype Antibody

Our Anti-Thyroid Hormone Receptor, α1/α2-Isotype primary antibody from PhosphoSolutions is mouse monoclonal. It detects human and rat Thyroid Hormone Receptor, α1/α2-Isotype and is Protein G purified. It is great for use in WB.

Product Specifications

Background

Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005; Chan and Kilby, 2000) . Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005) .

Synonyms

C-erbA-1 antibody, C-erbA-alpha antibody, EAR-7 antibody, ERBA 1 antibody, ERBA antibody, ERBA related 7 antibody, Nuclear receptor subfamily 1 group A member 1 antibody, THA_HUMAN antibody, THRA antibody, Thra1 antibody, Thra2 antibody, Thyroid hormone receptor alpha 1 antibody, Thyroid hormone receptor alpha 2 antibody, Thyroid hormone receptor alpha antibody, TR alpha 1 antibody, TR alpha 2 antibody, Tra1 antibody, Triiodothyronine receptor antibody, V-erbA-related protein 7 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

THRA

NCBI Gene ID

7067

UniProt

P10827

Host

Mouse

Reactivity

Human and Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the N-terminal region of human thyroid hormone receptor, α1/α2-isotype, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Human

Target

Thyroid Hormone Receptor, α1/α2-Isotype

Clonality

Monoclonal

Clone

1718

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

0.5 mg/ml

Format

Protein G Purified

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

50/58

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.