Anti-TAO2 (Ser181) Antibody

Our Anti-TAO2 (Ser181) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat TAO2 (Ser181) and is antigen affinity purified from pooled serum. It is great for use in WB.

Product Specifications

Background

In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001) . This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs (Chen et al., 2003) . Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser-181 is located within this domain.

Synonyms

1110033K02Rik antibody, B230344N16 antibody, hKFC C antibody, hKFC-C antibody, KIAA0881 antibody, Kinase from chicken homolog C antibody, MAP3K17 antibody, mKIAA0881 antibody, Prostate derived STE20 like kinase 1 antibody, Prostate derived STE20 like kinase PSK antibody, Prostate derived sterile 20 like kinase 1 antibody, Prostate-derived STE20-like kinase 1 antibody, PSK 1 antibody, PSK antibody, PSK-1 antibody, PSK1 antibody, PSK1 beta antibody, Serine/threonine protein kinase TAO2 antibody, Serine/threonine-protein kinase TAO2 antibody, TAO 1 antibody, TAO 2 antibody, TAO kinase 2 antibody, TAO1 antibody, TAO2 antibody, TAOK2 antibody, TAOK 2 antibody, Taok2 antibody, TAOK2_HUMAN antibody, Thousand and one amino acid protein 2 antibody, Thousand and one amino acid protein kinase antibody, UNQ2971/PRO7431 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

TAOK2

NCBI Gene ID

9344

UniProt

Q9UL54

Modification Site

Ser181

Host

Rabbit

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser181 of human TAO2, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Human

Target

TAO2 (Ser181)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

Lot Dependent

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Modification

Phosphorylated

Molecular Weight

120

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~120 kDa TAO2 phosphorylated at Ser181. Immunolabeling is completely eliminated by treatment with λ-phosphatase.