Anti-Synapsin I Antibody
Our Anti-Synapsin I rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Synapsin I and is neat pooled serum. It is great for use in WB.
Product Specifications
Background
Synapsin I plays a key role in synaptic plasticity in the brain (Feng et al., 2002; Nayak et al., 1996) . This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989; Stone et al., 1994) . Thus, Synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogenesis is regulated by phosphorylation (Jovanovic et al., 2001; Kao et al., 2002) .
Synonyms
Brain protein 4.1 antibody, SYN 1 antibody, SYN 1a antibody, SYN 1b antibody, SYN I antibody, SYN1 antibody, SYN1_HUMAN antibody, SYN1a antibody, SYN1b antibody, Synapsin 1 antibody, Synapsin I antibody, Synapsin-1 antibody, Synapsin1 antibody, SynapsinI antibody, SYNI antibody
Other Statements
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Gene Name
SYN1
NCBI Gene ID
281510
UniProt
P17599
Host
Rabbit
Reactivity
Human, Mouse, and Rat
Immunogen
Native protein purified from bovine brain.
Immunogen Type
Bovine
Target
Synapsin I
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
ELISA, WB
Format
Neat Pooled Serum
Form
Liquid
Buffer
Neat serum
Molecular Weight
78
Shipping Conditions
Blue Ice
Storage Conditions
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
WB Dilution
1:1000
Specificity
Specific for endogenous levels of the ~78 kDa synapsin I doublet. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.
Formulation
Unpurified pooled neat serum
Quality Control
Western blots performed on each lot.
Isotype
IgG
Curated Selection
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