Anti-SARS-CoV-2 S-Protein ACE2 Binding Domain Antibody

Our SARS-CoV-2 S-Protein ACE2 Binding Domain rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects and is antigen affinity purified. It is great for use in WB, ICC.

Product Specifications

Background

The novel SARS-coronavirus 2 (SARS-CoV-2) which causes the disease COVID-19 has been shown to utilize the SARS-CoV receptor ACE2 for entry into human cells (Hoffman, M. et al., Cell 2020) . The entry of a coronavirus into host cells is mediated by the viral surface-anchored transmembrane spike (S) glycoprotein which is composed of two functional subunits, S1 which binds the receptor and S2 which fuses the membrane (Walls, AC et.al., Cell 2020) . S1 contains a receptor-binding domain (RBD) which specifically recognizes ACE2 as its receptor (Wan, Y. et al., 2020) .

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

UniProt

P0DTC2

Host

Rabbit

Immunogen

Recombinant SARS-CoV-2 S-Protein construct containing the ACE2 binding domain expressed in and purified from E. coli.

Immunogen Type

SARS-CoV2

Target

SARS-CoV-2 S-Protein ACE2 Binding Domain

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB, ICC

Concentration

1 mg/ml

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 50% glycerol and 5 mm NaN3

Molecular Weight

25 or 142 full-length

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.