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Anti-Retinoid X Receptor, γ-Isotype Antibody

Our Anti-Retinoid X Receptor, γ-Isotype primary antibody from PhosphoSolutions is mouse monoclonal. It detects human and rat Retinoid X Receptor, γ-Isotype and is Protein G purified. It is great for use in WB.

Product Specifications

Background

Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005) . The Retinoid X Receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005) . RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005) .

Synonyms

MGC109416 antibody, NR2B3 antibody, Nuclear receptor subfamily 2 group B member 3 antibody, OTTHUMP00000060418 antibody, Retanoic X receptor gamma antibody, Retinoic acid receptor RXR gamma antibody, Retinoic acid receptor RXR-gamma antibody, Retinoid X receptor gamma antibody, RXR G antibody, RXR gamma antibody, RXRC antibody, Rxrg antibody, RXRG_HUMAN antibody, RXRgamma antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

RXRG

NCBI Gene ID

6258

UniProt

P48443

Host

Mouse

Reactivity

Human and Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the hinge region of human retinoid X receptor, γ-isotype, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Human

Target

Retinoid X Receptor, γ-Isotype

Clonality

Monoclonal

Clone

1373

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

0.5 mg/ml

Format

Protein G Purified

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

48

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~48 kDa RXR-γ isotype.

Formulation

Prepared from tissue culture supernatant by ammonium sulfate precipitation followed by purification on a Protein G column.

Quality Control

Western blots performed on each lot.

Species

Bovine, Mouse, Non-Human Primate

Isotype

IgG1

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