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Anti-Retinoid X Receptor, ß-Isotype Antibody

Our Anti-Retinoid X Receptor, ß-Isotype primary antibody from PhosphoSolutions is mouse monoclonal. It detects mouse and rat Retinoid X Receptor, ß-Isotype and is Protein G purified. It is great for use in WB.

Product Specifications

Background

Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005) . The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005) . RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005) .

Synonyms

DAUD I6 antibody, DAUDI6 antibody, H 2RIIBP antibody, H2RIIBP antibody, MGC1831 antibody, MHC class I promoter binding protein antibody, NR2B2 antibody, nuclear receptor subfamily 2 group B member 2 antibody, RCoR 1 antibody, RCoR1 antibody, Retinoic acid receptor RXR beta antibody, RXR beta antibody, RXRB antibody, RXRbeta antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

RXRB

NCBI Gene ID

6257

UniProt

P28702

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the mouse retinoid X receptor, β- isotype, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Mouse

Target

Retinoid X Receptor, ß-Isotype

Clonality

Monoclonal

Clone

147

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

0.5 mg/ml

Format

Protein G Purified

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

48

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~48 kDa RXR-beta protein.

Formulation

Prepared from tissue culture supernatant by ammonium sulfate precipitation followed by purification on a Protein G column.

Quality Control

Western blots performed on each lot.

Isotype

IgG1

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