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Anti-Rabphilin 3A Antibody

Our Anti-Rabphilin 3A rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects rat Rabphilin 3A and is antigen affinity purified from pooled serum. It is great for use in WB.

Product Specifications

Background

Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994; Li et al., 1994) . The expression of rabphilin 3A is reduced in an animal model of Huntington’s disease (Smith et al., 2005) . Rabphilin can be phosphorylated at Ser-234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995; Foletti and Scheller, 2001) .

Synonyms

Exophilin 1 antibody, Exophilin-1 antibody, Exophilin1 antibody, KIAA0985 antibody, Rabphilin 3A homolog antibody, Rabphilin-3A antibody, Rabphilin3A antibody, RP3A antibody, RP3A_HUMAN antibody, Rph 3a antibody, Rph3a antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

RPH3A

NCBI Gene ID

171039

UniProt

P47709

Host

Rabbit

Reactivity

Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat rabphilin 3A conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

Rabphilin 3A

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

Lot Dependent

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

82

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~82 kDa rabphilin 3A protein.

Formulation

Prepared from pooled rabbit serum by affinity purification via chromatography on an affinity column made with the C-terminal peptide used as antigen.

Quality Control

Western blots performed on each lot.

Species

Bovine, Canine, Human, Non-Human Primate, Mouse

Isotype

IgG

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