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Anti-PSD-95 Antibody

Our Anti-PSD-95 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects mouse and rat PSD-95 and is antigen affinity purified from pooled serum. It is great for use in WB.

Product Specifications

Background

PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004) . Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004) .

Synonyms

Discs large homolog 4 antibody, Disks large homolog 4 antibody, DLG 4 antibody, Dlg4 antibody, DLG4_HUMAN antibody, FLJ97752 antibody, FLJ98574 antibody, Human post synaptic density protein 95 antibody, Post synaptic density protein 95 antibody, Postsynaptic density protein 95 antibody, PSD 95 antibody, PSD-95 antibody, PSD95 antibody, SAP 90 antibody, SAP-90 antibody, SAP90 antibody, Synapse associated protein 90 antibody, Synapse-associated protein 90 antibody, Tax interaction protein 15 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

DLG4

NCBI Gene ID

29495

UniProt

P31016

Host

Rabbit

Reactivity

Mouse and Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

PSD-95

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

Lot Dependent

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

95

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~95 kDa PSD-95 protein.

Formulation

Prepared from pooled rabbit serum by affinity purification using a column with the N-terminal peptide used as antigen.

Quality Control

Western blots performed on each lot.

Species

Bovine, Human, Non-Human Primate, Zebrafish

Isotype

IgG

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