Anti-Potassium Channel, Voltage-Gated, Kv3.1 Subunit (Ser503) Antibody

Our Anti-Potassium Channel, Voltage-Gated, Kv3.1 Subunit (Ser503) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects hamster, mouse and rat Potassium Channel, Voltage-Gated, Kv3.1 Subunit (Ser503) and is antigen affinity purified from pooled serum. It is great for use in WB, IHC, ICC.

Product Specifications

Background

Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995; Pongs, 1999; Blaine and Ribera, 1998; Burger and Ribera, 1996) . The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999) . Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004) .

Synonyms

C230009H10Rik antibody, FLJ41162 antibody, FLJ42249 antibody, FLJ43491 antibody, Kcnc1 antibody, KCNC1 antibody, KCNC1_HUMAN antibody, Kcr2 1 antibody, KShIIIB antibody, Kv3.1 antibody, Kv4 antibody, MGC129855 antibody, NGK2 antibody, Potassium voltage-gated channel subfamily C member 1 antibody, Shaw antibody, Voltage gated potassium channel antibody, Voltage gated potassium channel subunit Kv3.1 antibody, Voltage-gated potassium channel subunit Kv3.1 antibody, Voltage-gated potassium channel subunit Kv4 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

KCNC1

NCBI Gene ID

25327

UniProt

P25122

Modification Site

Ser503

Host

Rabbit

Reactivity

Hamster, Mouse and Rat

Immunogen

The antigen is a phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser503 of the rat voltage-gated potassium channel Kv3.1, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

Potassium Channel, Voltage-Gated, Kv3.1 Subunit (Ser503)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB, IHC, ICC

Concentration

Lot Dependent

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Modification

Phosphorylated

Molecular Weight

100

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.