Anti-Potassium Channel, Voltage Gated, Kv2.2 Subunit Antibody

Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999) . Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK) channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety of non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993; Yan et al., 2004; Michaelevski et al., 2003) . Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998; Burger and Ribera, 1996) .

Delayed rectifier potassium channel protein antibody, KCNB2 antibody, KCNB2_HUMAN antibody, potassium channel Kv2.2 antibody, potassium voltage gated channel subfamily B member 2 antibody, Potassium voltage-gated channel subfamily B member 2 antibody, Voltage-gated potassium channel subunit Kv2.2 antibody

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Synthetic peptide from the subunit region of the voltage gated potassium channel from the rat and Xenopus Kv2.2 sequence, conjugated to keyhole limpet hemocyanin (KLH) .