Anti-Phospholipase C β2 (PLC-β2) Antibody

Our Anti-Phospholipase C β2 (PLC-β2) rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human and non-human primate Phospholipase C β2 (PLC-β2) and is antigen affinity purified from pooled serum. It is great for use in IHC.

Product Specifications

Background

Phospholipases are quite common enzymes that are present in a broad range of organisms, including bacteria, yeast, plants, animals, and viruses. Phospholipase C (PLC) constitutes a class of enzymes that cleave phospholipids on the diacylglycerol (DAG) side of the phosphodiester bond (Cocco et al., 2015) . A growing body of evidence supports the role of phospholipase C (PLC) in the invasion and metastasis of different tumors, including breast cancer (Bertagnolo et al., 2006) . PLC-β2 has been shown to be required for sweet, umami and bitter taste perception in mammals (Zhang et al., 2003) . Data also suggests that PLC-β2 serves an unappreciated role assembling components of the p38MAPK signaling module (Barr et al., 2002) .

Synonyms

1-phosphatidylinositol-4 antibody, 1-phosphatidylinositol-4 5-bisphosphate phosphodiesterase beta-2 antibody, 5-bisphosphate phosphodiesterase beta-2 antibody, FLJ38135 antibody, Phosphoinositide phospholipase C-beta-2 antibody, Phospholipase C-beta-2 antibody, PLC-beta-2 antibody, Plcb2 antibody, PLCB2_HUMAN antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

PLCB2

NCBI Gene ID

5330

UniProt

Q00722

Host

Rabbit

Reactivity

Human and Non-Human Primate

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region of human PLC β2.

Immunogen Type

Human

Target

Phospholipase C β2 (PLC-β2)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, IHC

Concentration

Lot Dependent

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

135

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.