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Anti-Olig2 Antibody

Our Anti-Olig2 primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human, mouse, and rat Olig2 and is protein a purified. It is great for use in WB, IHC, ICC, IP.

Product Specifications

Background

Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007)

Synonyms

Basic domain helix loop helix protein class B 1 antibody, Basic helix loop helix protein class B 1 antibody, BHLHB antibody, bHLHB1 antibody, bHLHe19 antibody, Class B basic helix loop helix protein 1 antibody, Class B basic helix-loop-helix protein 1 antibody, class E basic helix loop helix protein 19 antibody, Class E basic helix-loop-helix protein 19 antibody, Human protein kinase C binding protein RACK17 antibody, Olig2 antibody, OLIG2_HUMAN antibody, Oligo2 antibody, Oligodendrocyte lineage transcription factor 2 antibody, Oligodendrocyte specific bHLH transcription factor 2 antibody, Oligodendrocyte transcription factor 2 antibody, OTTHUMP00000067569 antibody, OTTHUMP00000067570 antibody, PRKCBP2 antibody, Protein kinase C binding protein 2 antibody, Protein kinase C binding protein RACK17 antibody, Protein kinase C-binding protein 2 antibody, Protein kinase C-binding protein RACK17 antibody, RACK17 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

OLIG2

NCBI Gene ID

50913

UniProt

Q9EQW6

Host

Rabbit

Reactivity

Human, Mouse, and Rat

Immunogen

Recombinant mouse Olig2.

Immunogen Type

Mouse

Target

Olig2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB, IHC, ICC, IP

Concentration

0.5 mg/ml

Format

Protein A purified

Form

Liquid

Buffer

100 mM Glycine, 200 mM Tris, pH 8.0

Molecular Weight

27

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

IHC Dilution

1:200-1:1000

WB Dilution

1:3000

IP Dilution

1:500-1:1000

Specificity

Specific for endogenous levels of the ~32 kDa Olig2 protein.

Formulation

Protein A purified rabbit serum

ICC Dilution

1:1000

Quality Control

Western blots performed on each lot.

Isotype

IgG

Curated Selection

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