Anti-Olig2 Antibody
Our Anti-Olig2 primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human, mouse, and rat Olig2 and is protein a purified. It is great for use in WB, IHC, ICC, IP.
Product Specifications
Background
Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007)
Synonyms
Basic domain helix loop helix protein class B 1 antibody, Basic helix loop helix protein class B 1 antibody, BHLHB antibody, bHLHB1 antibody, bHLHe19 antibody, Class B basic helix loop helix protein 1 antibody, Class B basic helix-loop-helix protein 1 antibody, class E basic helix loop helix protein 19 antibody, Class E basic helix-loop-helix protein 19 antibody, Human protein kinase C binding protein RACK17 antibody, Olig2 antibody, OLIG2_HUMAN antibody, Oligo2 antibody, Oligodendrocyte lineage transcription factor 2 antibody, Oligodendrocyte specific bHLH transcription factor 2 antibody, Oligodendrocyte transcription factor 2 antibody, OTTHUMP00000067569 antibody, OTTHUMP00000067570 antibody, PRKCBP2 antibody, Protein kinase C binding protein 2 antibody, Protein kinase C binding protein RACK17 antibody, Protein kinase C-binding protein 2 antibody, Protein kinase C-binding protein RACK17 antibody, RACK17 antibody
Other Statements
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Gene Name
OLIG2
NCBI Gene ID
50913
UniProt
Q9EQW6
Host
Rabbit
Reactivity
Human, Mouse, and Rat
Immunogen
Recombinant mouse Olig2.
Immunogen Type
Mouse
Target
Olig2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
ELISA, WB, IHC, ICC, IP
Concentration
0.5 mg/ml
Format
Protein A purified
Form
Liquid
Buffer
100 mM Glycine, 200 mM Tris, pH 8.0
Molecular Weight
27
Shipping Conditions
Blue Ice
Storage Conditions
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
IHC Dilution
1:200-1:1000
WB Dilution
1:3000
IP Dilution
1:500-1:1000
Specificity
Specific for endogenous levels of the ~32 kDa Olig2 protein.
Formulation
Protein A purified rabbit serum
ICC Dilution
1:1000
Quality Control
Western blots performed on each lot.
Isotype
IgG
Curated Selection
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