Anti-NG2/CSPG4 Antibody

Our NG2/CSPG4 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects NG2/CSPG4 and is antigen affinity purified from pooled serum. It is great for use in WB, IHC.

Product Specifications

Background

Neuron-glial antigen 2 (NG2) is a chondroitin sulfate proteoglycan that is encoded by the CSPG4 gene in humans. It is an excellent oligodendrocyte marker. NG2 is a hallmark protein of oligodendrocyte progenitor cells (OPCs) and has been linked with familial schizophrenia (de Vrij, F.M., et al, 2018) . NG2 also plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. It represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells (Luo, W., et al, 2006) . NG2 localizes at the apical plasma membrane and relocalizes to the lamellipodia of astrocytoma upon PRKCA phosphorylation.

Synonyms

4732461B14Rik antibody, AN2 antibody, AN2 proteoglycan antibody, Chondroitin sulfate proteoglycan 4 (melanoma-associated) antibody, Chondroitin sulfate proteoglycan 4 antibody, Chondroitin sulfate proteoglycan NG2 antibody, Cspg4 antibody, Cspg4 chondroitin sulfate proteoglycan 4 antibody, CSPG4_HUMAN antibody, HMW-MAA antibody, HSN tumor-specific antigen antibody, Kiaa4232 antibody, MCSP antibody, MCSPG antibody, MEL-CSPG antibody, Melanoma chondroitin sulfate proteoglycan antibody, Melanoma-associated chondroitin sulfate proteoglycan antibody, MELCSPG antibody, MSK16 antibody, NG2 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

CSPG4

NCBI Gene ID

1464

UniProt

Q6UVK1

Host

Rabbit

Reactivity

Human, Mouse, and Rat

Immunogen

Recombinant human NG2/CSPG4 protein

Immunogen Type

Human

Target

NG2/CSPG4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB, IHC

Concentration

Lot Dependent

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

250

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.