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Anti-GRIP1 Associated Protein 1 (GRASP1) Antibody

Our Anti-GRIP1 Associated Protein 1 (GRASP1) rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects mouse and rat GRIP1 Associated Protein 1 (GRASP1) and is antigen affinity purified from pooled serum. It is great for use in WB.

Product Specifications

Background

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000) . Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000) .

Synonyms

DKFZp434P0630 antibody, DXImx47e antibody, GRAP1_HUMAN antibody, GRASP 1 antibody, GRASP-1 antibody, GRASP1 antibody, GRIP 1 associated protein 1 antibody, GRIP associated protein 1 antibody, GRIP1 associated protein 1 antibody, GRIP1-associated protein 1 antibody, GRIPAP 1 antibody, GRIPAP1 antibody, KIAA1167 antibody, MGC126593 antibody, MGC126595 antibody, MPMGp800B12492Q3 antibody, Sfc10 antibody, TAMALIN antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

GRIPAP1

NCBI Gene ID

116493

UniProt

Q9JHZ4

Host

Rabbit

Reactivity

Mouse and Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GRASP1, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

GRIP1 Associated Protein 1 (GRASP1)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

Lot Dependent

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

95

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~95 kDa GRASP1 protein.

Formulation

Prepared from pooled rabbit serum by affinity purification via chromatography on an affinity column made with the C-terminal peptide used as antigen.

Quality Control

Western blots performed on each lot.

Species

Bovine, Canine, Human

Isotype

IgG

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