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Anti-GluR2 Antibody

Our Anti-GluR2 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects rat GluR2 and is antigen affinity purified from pooled serum. It is great for use in WB.

Product Specifications

Background

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR) . The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994) . The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003) .

Synonyms

AMPA 2 antibody, AMPA selective glutamate receptor 2 antibody, AMPA-selective glutamate receptor 2 antibody, AMPA2 antibody, GluA2 antibody, GLUR 2 antibody, GLUR B antibody, GluR K2 antibody, GluR-2 antibody, GluR-B antibody, GluR-K2 antibody, GLUR2 antibody, GLURB antibody, Glutamate receptor 2 antibody, Glutamate receptor ionotropic AMPA 2 antibody, Glutamate receptor ionotropic antibody, Gria2 antibody, GRIA2_HUMAN antibody, HBGR2 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

GRIA2

NCBI Gene ID

29627

UniProt

P19491

Host

Rabbit

Reactivity

Rat

Immunogen

Synthetic peptide corresponding to amino acid residues specific to GluR2, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

GluR2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

Lot Dependent

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

100

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Product Datasheet

https://cdn.shopify.com/s/files/1/0520/9063/4413/files/900-GluR2.pdf

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~100 kDa GluR2 protein.

Formulation

Prepared from rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Species

Chicken, Human, Non-Human Primate, Mouse, Zebrafish

Isotype

IgG

Curated Selection

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