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Anti-GluR1 Antibody

Our Anti-GluR1 primary antibody from PhosphoSolutions is mouse monoclonal. It detects mouse and rat GluR1 and is Protein G purified. It is great for use in WB.

Product Specifications

Background

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR) . The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994) .

Synonyms

GLUR 1 antibody, GLUR A antibody, AMPA 1 antibody, AMPA selective glutamate receptor 1 antibody, AMPA-selective glutamate receptor 1 antibody, GluA1 antibody, GLUH1 antibody, GluR K1 antibody, GluR-1 antibody, GluR-A antibody, GluR-K1 antibody, GLUR1 antibody, GLURA antibody, GluRK1 antibody, Glutamate receptor 1 antibody, Glutamate receptor ionotropic AMPA 1 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor, ionotropic, AMPA 1 antibody, Gria1 antibody, GRIA1_HUMAN antibody, HBGR1 antibody, MGC133252 antibody, OTTHUMP00000160643 antibody, OTTHUMP00000165781 antibody, THUMP00000224241 antibody, OTTHUMP00000224242 antibody, OTTHUMP00000224243 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

GRIA1

NCBI Gene ID

50592

UniProt

P19490

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat GluR1, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

GluR1

Clonality

Monoclonal

Clone

RH95

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

Lot Dependent

Format

Protein G Purified

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

100

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~105 kDa GluR1 protein.

Formulation

Protein G purified culture supernatant.

Quality Control

Western blots performed on each lot.

Isotype

IgG2a

Curated Selection

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