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Anti-GABA Transporter (GAT) 2 Antibody

Our Anti-GABA Transporter (GAT) 2 primary antibody from PhosphoSolutions is rabbit polyclonal. It detects mouse and rat GABA Transporter (GAT) 2 and is affinity purified. It is great for use in WB, IHC.

Product Specifications

Background

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABA-A receptor (GABA-A-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999)

Synonyms

GABA transport protein antibody, GAT 2 antibody, GAT-2 antibody, GAT2 antibody, GAT3 antibody, S6A13_HUMAN antibody, SLC6A13 antibody, Sodium- and chloride-dependent GABA transporter 2 antibody, Solute carrier family 6 (Neurotransmitter transporter GABA), member 13 antibody, Solute carrier family 6 member 13 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

SLC6A13

NCBI Gene ID

171163

UniProt

P31646

Host

Rabbit

Reactivity

Mouse and Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GAT2, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

GABA Transporter (GAT) 2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB, IHC

Concentration

Lot Dependent

Format

Affinity Purified

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

67

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

IHC Dilution

1:100-200

WB Dilution

1:100-200

Specificity

Specific for endogenous levels of the ~82 kDa GAT-2 protein.

Formulation

Prepared from rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Isotype

IgG

Curated Selection

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