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Anti-FTO (Fat mass and obesity related protein) Antibody

Our Anti-FTO (Fat mass and obesity related protein) primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, mouse, and rat FTO (Fat mass and obesity related protein) and is Protein G purified. It is great for use in WB, ICC.

Product Specifications

Background

The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008) . Deletion analysis of FTO gene in mice showed that FTO is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009) .

Synonyms

AlkB homolog 9 antibody, ALKBH9 antibody, Alpha-ketoglutarate-dependent dioxygenase FTO antibody, AW743446 antibody, Fat mass and obesity-associated protein antibody, FATSO, MOUSE, HOMOLOG OF antibody, Fto antibody, FTO_HUMAN antibody, GDFD antibody, KIAA1752 antibody, mKIAA1752 antibody, Protein fatso antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

FTO

NCBI Gene ID

79068

UniProt

Q9C0B1

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat FTO, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

FTO (Fat mass and obesity related protein)

Clonality

Monoclonal

Clone

5-2H10

Conjugation

Unconjugated

Applications

ELISA, WB, ICC

Concentration

1 mg/mL

Format

Protein G Purified

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

58

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~58 kDa FTO protein.

Formulation

Protein G purified culture supernatant.

ICC Dilution

1:100-1:600

Quality Control

Western blots performed on each lot.

Species

Bovine, Canine, Non-Human Primate, Sheep

Isotype

IgG2a

Curated Selection

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