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Anti-Doublecortin Antibody

Our Anti-Doublecortin primary antibody from PhosphoSolutions is mouse monoclonal. It detects bovine, human, mouse, and rat Doublecortin and is Protein G purified. It is great for use in WB, IHC, ICC.

Product Specifications

Background

Doublecortin, or DCX, is a microtubule associated protein that is expressed almost exclusively in very early neuronal development (Brown et al., 2003), making it an excellent marker for developing neuronal cells. Defects in the DCX gene lead to X-linked lissencephaly which is characterized by a lack of normal folds on the surface of the brain resulting in a smooth cerebral cortex caused by abnormal migration of neurons during development (des Portes et al., 1998; Gleeson et al., 1998) .

Synonyms

DBCN antibody, Dbct antibody, DC antibody, DCX antibody, DCX_HUMAN antibody, Doublecortex antibody, Doublin antibody, FLJ51296 antibody, Lis X antibody, Lis-X antibody, Lissencephalin X antibody, Lissencephalin-X antibody, Lissencephaly X linked antibody, Lissencephaly X linked doublecortin antibody, LISX antibody, Neuronal migration protein doublecortin antibody, OTTHUMP00000023859 antibody, OTTHUMP00000023860 antibody, OTTHUMP00000216315 antibody, OTTHUMP00000216316 antibody, SCLH antibody, XLIS antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

DCX

NCBI Gene ID

1641

UniProt

O43602

Host

Mouse

Reactivity

Bovine, Human, Mouse, and Rat

Immunogen

Full length recombinant human protein expressed in and purified from E. coli.

Immunogen Type

Human

Target

Doublecortin

Clonality

Monoclonal

Clone

3 E1

Conjugation

Unconjugated

Applications

ELISA, WB, IHC, ICC

Concentration

1 mg/ml

Format

Protein G Purified

Form

Liquid

Buffer

PBS + 50% glycerol and 5 mm NaN3

Molecular Weight

35, 45

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

IHC Dilution

1:1000

WB Dilution

1:5000

Specificity

Specific for endogenous levels of the ~35 kDa & ~45 kDa doublecortin protein.

Formulation

Protein G purified culture supernatant.

ICC Dilution

1:1000

Quality Control

Western blots performed on each lot.

Isotype

IgG2A

Curated Selection

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