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Anti-Dopamine ß-Hydroxylase, C-Terminus Antibody

Our Anti-Dopamine ß-Hydroxylase, C-Terminus sheep polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and non-human primate Dopamine ß-Hydroxylase, C-Terminus and is antigen affinity purified from pooled serum. It is great for use in WB.

Product Specifications

Background

DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999) . The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001) .

Synonyms

Dbh antibody, DBM antibody, Dopamine beta hydroxylase antibody, Dopamine beta monooxygenase antibody, Dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody, Dopamine beta-monooxygenase antibody, DOPO_HUMAN antibody, OTTHUMP00000022501 antibody, Soluble dopamine beta-hydroxylase antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

DBH

NCBI Gene ID

1621

UniProt

P09172

Host

Sheep

Reactivity

Human, Mouse, and Non-Human Primate

Immunogen

Synthetic peptide from the C-terminal region of human dopamine β-hydroxylase (DBH), conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Human

Target

Dopamine ß-Hydroxylase, C-Terminus

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

0.3 mg/mL

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

75

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~75 kDa DBH protein.

Formulation

Prepared from pooled sheep serum by affinity purification using a column matrix to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Isotype

IgG

Curated Selection

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