Anti-DOPA Decarboxylase Antibody

Our Anti-DOPA Decarboxylase rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects bovine, canine, guinea pig, human, rabbit, rat, and sheep DOPA Decarboxylase and is antigen affinity purified from pooled serum. It is great for use in WB.

Product Specifications

Background

DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003) . It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999) .

Synonyms

AADC antibody, Aromatic L Amino Acid Decarboxylase antibody, Aromatic-L-amino-acid decarboxylase antibody, DDC antibody, DDC_HUMAN antibody, DOPA decarboxylase (aromatic L-amino acid decarboxylase) antibody, DOPA decarboxylase antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

DDC

NCBI Gene ID

1644

UniProt

P20711

Host

Rabbit

Reactivity

Bovine, Canine, Guinea Pig, Human, Rabbit, Rat, and Sheep

Immunogen

Synthetic peptide from N-terminus region of human DOPA decarboxylase (DDC), conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Human

Target

DOPA Decarboxylase

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB

Concentration

0.15 mg/mL

Format

Antigen Affinity Purified from Pooled Serum

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~55 kDa DDC protein.

Formulation

Prepared from pooled rabbit serum by affinity purification using an AminoLink® Plus column matrix to which purified, recombinant bovine DDC was coupled.