Anti-Clavesin Antibody

Our Anti-Clavesin primary antibody from PhosphoSolutions is rabbit polyclonal. It detects rat Clavesin and is affinity purified. It is great for use in WB, ICC.

Product Specifications

Background

Clavesin (clathrin vesicle associated Sec14 protein) is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects (Katoh et al., 2009) . Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state (Zhao et al., 2008) .

Synonyms

4 antibody, C6orf212 antibody, C6orf213 antibody, Clavesin 1 antibody, Clavesin 2 antibody, CRALBPL antibody, FLJ37248 antibody, MGC120572 antibody, MGC34646 antibody, OTTHUMP00000017122 antibody, Retinaldehyde binding protein 1 like 1 antibody, Retinaldehyde binding protein 1 like 2 antibody, RLBP1L1 antibody, RLBP1L2 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

CLVS1/2

NCBI Gene ID

366311

UniProt

A6JFQ6

Host

Rabbit

Reactivity

Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat Clavesin 1, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

Clavesin

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB, ICC

Concentration

Lot Dependent

Format

Affinity Purified

Form

Liquid

Buffer

PBS + 50% glycerol

Molecular Weight

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~35 kDa clavesin 1/2 protein doublet. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are clavesin 1 and 2, respectively.