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Anti-c-FOS Antibody

Our Anti-c-FOS primary antibody from PhosphoSolutions is mouse monoclonal. It detects bovine, human, mouse, and rat c-FOS and is Protein G purified. It is great for use in WB, IHC, ICC.

Product Specifications

Background

C-FOS is a member of the FOS transcription factor family which forms dimers with c-JUN to produce the Activator Protein 1 (AP-1) complex which plays a key role in critical cellular processes such as cell proliferation, differentiation and apoptosis (Chiu et al., 1988) . c-FOS expression has been demonstrated to be a useful marker of neuronal activation as it is rapidly induced following various stimuli (Hoffman et al., 1993) . Additionally, c-FOS has been shown to be overexpressed in a variety of malignant tumor types (Milde-Langosch 2005) .

Synonyms

Activator protein 1 antibody, AP 1 antibody, C FOS antibody, Cellular oncogene c fos antibody, Cellular oncogene fos antibody, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody, FBJ murine osteosarcoma viral oncogene homolog antibody, FBJ murine osteosarcoma viral v fos oncogene homolog antibody, FBJ Osteosarcoma Virus antibody, FOS antibody, FOS protein antibody, FOS_HUMAN antibody, G0 G1 switch regulatory protein 7 antibody, G0/G1 switch regulatory protein 7 antibody, G0S7 antibody, Oncogene FOS antibody, p55 antibody, proto oncogene c Fos antibody, Proto oncogene protein c fos antibody, Proto-oncogene c-Fos antibody, fos FBJ murine osteosarcoma viral oncogene homolog antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

FOS

NCBI Gene ID

2353

UniProt

P01100

Host

Mouse

Reactivity

Bovine, Human, Mouse, and Rat

Immunogen

Recombinant full length human c-FOS expressed in and purified from E. Coli.

Immunogen Type

Human

Target

C-FOS

Clonality

Monoclonal

Clone

2H2

Conjugation

Unconjugated

Applications

ELISA, WB, IHC, ICC

Concentration

1 mg/ml

Format

Protein G Purified

Form

Liquid

Buffer

PBS + 50% glycerol and 5 mM NaN3

Molecular Weight

50

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

IHC Dilution

1:1000

WB Dilution

1:2000

Specificity

Specific for endogenous levels of the ~50 kDa c-FOS protein.

Formulation

Protein G purified culture supernatant.

ICC Dilution

1:1000

Quality Control

Western blots performed on each lot.

Isotype

IgG1

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