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Anti-CD75 (Transferrin receptor) Antibody

Our Anti-CD75 (Transferrin receptor) mouse monoclonal primary antibody from PhosphoSolutions is produced in-house. It detects CD75 and is Protein L purified. It is great for use in WB, IHC.

Product Specifications

Background

CD75, also known as β-galactoside α2,6-sialyltransferase, is a specific carbohydrate antigen that is predominantly expressed on B cell lymphocytes. β-galactoside α2,6-sialyltransferase is an enzyme that catalyzes the addition of sialic acid to growing carbohydrate chains of glycoproteins (Guy, K., et al, 1991) . CD75 is a major component of the lymphoid cell surface that serves as a ligand for cell adhesion molecules (Paulson, J.C., et al, 1989) . The LN-1 clone reacts positively with red blood cell precursors of the bone marrow, ciliated epithelial cells of the bronchus, distal tubular cells of the kidney, and ductal cells from several organs including the breast and prostate (Epstein, A.L., et al, 1984) . CD75 has been shown to be superior to other B cell markers in detecting lymphocyte predominant cells through their cytoplasmic and membraneous staining, especially in typical nodular lymphocyte-predominant Hodgkin lymphoma patterns (Carbone, A., et al, 2014) .

Synonyms

6 sialyltransferase antibody, 6-sialyltransferase 1 antibody, 6-ST 1 antibody, Alpha 2 antibody, Alpha 2,6 ST 1 antibody, Alpha 2,6 ST antibody, B cell antigen CD75 antibody, B-cell antigen CD75 antibody, Beta galactoside alpha 2,6 sialyltransferase 1 antibody, Beta-galactoside alpha-2 antibody, CMP N acetylneuraminate beta galactosamide alpha 2,6 sialyltransferase 1 antibody, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2 antibody, MGC48859 antibody, Sialyltransferase 1 (beta galactoside alpha 2,6 sialyltransferase) antibody, Sialyltransferase 1 antibody, SIAT1 antibody, SIAT1_HUMAN antibody, ST6 beta galactosamide alpha 2,6 sialyltranferase 1 antibody, ST6Gal I antibody, ST6GAL1 antibody, ST6GalI antibody, ST6N antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

ST6GAL1

NCBI Gene ID

6480

UniProt

P15907

Host

Mouse

Reactivity

Human

Immunogen

Nuclei isolated from pokeweed mitogen-stimulated human peripheral blood lymphocytes.

Immunogen Type

Human

Target

CD75

Clonality

Monoclonal

Clone

LN1

Conjugation

Unconjugated

Applications

ELISA, WB, IHC

Concentration

Lot Dependent

Format

Protein L purified

Form

Liquid

Buffer

PBS

Molecular Weight

35

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

IHC Dilution

1:100

WB Dilution

1:100

Specificity

Specific for endogenous levels of the ~35 kDa CD75 protein.

Formulation

Protein L purified culture supernatant.

Quality Control

Western blots performed on each lot.

Isotype

IgM

Curated Selection

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