Anti-CD75 (Transferrin receptor) Antibody
Our Anti-CD75 (Transferrin receptor) mouse monoclonal primary antibody from PhosphoSolutions is produced in-house. It detects CD75 and is Protein L purified. It is great for use in WB, IHC.
Product Specifications
Background
CD75, also known as β-galactoside α2,6-sialyltransferase, is a specific carbohydrate antigen that is predominantly expressed on B cell lymphocytes. β-galactoside α2,6-sialyltransferase is an enzyme that catalyzes the addition of sialic acid to growing carbohydrate chains of glycoproteins (Guy, K., et al, 1991) . CD75 is a major component of the lymphoid cell surface that serves as a ligand for cell adhesion molecules (Paulson, J.C., et al, 1989) . The LN-1 clone reacts positively with red blood cell precursors of the bone marrow, ciliated epithelial cells of the bronchus, distal tubular cells of the kidney, and ductal cells from several organs including the breast and prostate (Epstein, A.L., et al, 1984) . CD75 has been shown to be superior to other B cell markers in detecting lymphocyte predominant cells through their cytoplasmic and membraneous staining, especially in typical nodular lymphocyte-predominant Hodgkin lymphoma patterns (Carbone, A., et al, 2014) .
Synonyms
6 sialyltransferase antibody, 6-sialyltransferase 1 antibody, 6-ST 1 antibody, Alpha 2 antibody, Alpha 2,6 ST 1 antibody, Alpha 2,6 ST antibody, B cell antigen CD75 antibody, B-cell antigen CD75 antibody, Beta galactoside alpha 2,6 sialyltransferase 1 antibody, Beta-galactoside alpha-2 antibody, CMP N acetylneuraminate beta galactosamide alpha 2,6 sialyltransferase 1 antibody, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2 antibody, MGC48859 antibody, Sialyltransferase 1 (beta galactoside alpha 2,6 sialyltransferase) antibody, Sialyltransferase 1 antibody, SIAT1 antibody, SIAT1_HUMAN antibody, ST6 beta galactosamide alpha 2,6 sialyltranferase 1 antibody, ST6Gal I antibody, ST6GAL1 antibody, ST6GalI antibody, ST6N antibody
Other Statements
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Gene Name
ST6GAL1
NCBI Gene ID
6480
UniProt
P15907
Host
Mouse
Reactivity
Human
Immunogen
Nuclei isolated from pokeweed mitogen-stimulated human peripheral blood lymphocytes.
Immunogen Type
Human
Target
CD75
Clonality
Monoclonal
Clone
LN1
Conjugation
Unconjugated
Applications
ELISA, WB, IHC
Concentration
Lot Dependent
Format
Protein L purified
Form
Liquid
Buffer
PBS
Molecular Weight
35
Shipping Conditions
Blue Ice
Storage Conditions
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
IHC Dilution
1:100
WB Dilution
1:100
Specificity
Specific for endogenous levels of the ~35 kDa CD75 protein.
Formulation
Protein L purified culture supernatant.
Quality Control
Western blots performed on each lot.
Isotype
IgM
Curated Selection
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