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Anti-Arginase I (ARG1) Antibody

Our Anti-Arginase I (ARG1) primary antibody from PhosphoSolutions is chicken polyclonal. It detects guinea pig, human, mouse, and rat Arginase I (ARG1) and is total IgY fraction. It is great for use in WB, IHC.

Product Specifications

Background

Arginase I, a cytosolic enzyme, is highly expressed in the liver and is a component of the urea cycle (Jenkinson et al, 1996) . There are two isoforms of arginase, both catalyze the conversion of arginine to ornithine and urea, but differ based on subcellular localization, tissue distribution, and enzymatic properties (Jenkinson et al, 1996) . Arginase I has been identified in macrophages in response to various pathogen exposures causing an upregulation of inducible nitric oxide synthase, iNOS, yielding increased levels of nitric oxide (Morris et al, 1998) and inflammation (Poljakovic et al, 2007) .

Synonyms

A I antibody, Al antibody, ARG 1 antibody, arg1 antibody, ARGI1_HUMAN antibody, Arginase 1 antibody, Arginase liver antibody, Arginase type I antibody, Arginase liver antibody, Arginase-1 antibody, Arginase1 antibody, Liver type arginase antibody, Liver-type arginase antibody, Type I arginase antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

ARG1

NCBI Gene ID

29221

UniProt

P07824

Host

Chicken

Reactivity

Guinea Pig, Human, Mouse, and Rat

Immunogen

Full-length recombinant rat liver arginase I expressed in and purified from E. Coli.

Immunogen Type

Rat

Target

Arginase I (ARG1)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB, IHC

Concentration

Lot Dependent

Format

Total IgY fraction

Form

Liquid

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Molecular Weight

35/38

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

IHC Dilution

1:500

WB Dilution

1:1000

Specificity

Specific for endogenous levels of the ~35-38 kDa arginase I protein.

Formulation

Total IgY fraction.

Quality Control

Western blots performed on each lot.

Isotype

IgY

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