Anti-Alpha II Spectrin Antibody

Our Anti-Alpha II Spectrin primary antibody from PhosphoSolutions is mouse monoclonal. It detects bovine, human, mouse, and rat Alpha II Spectrin and is Protein G purified. It is great for use in WB, IHC, ICC.

Product Specifications

Background

The spectrin family of cytoskeletal proteins is comprised of 2 alpha genes (α1 and α2) and five beta genes (β1-β5) . Spectrins have been shown to function as scaffolding proteins in mechanical support of the plasma membrane as well as bind other membrane proteins and lipids (Bennett and Baines 2001) . Defects in spectrin genes have been linked to some forms of hereditary spherocytosis, a type of auto-hemolytic anemia which is characterized by spherical red blood cells that are more prone to lysis (Eber and Lux 2004) .

Synonyms

(ALPHA) II-SPECTRIN antibody, Alpha-II spectrin antibody, brain antibody, EIEE5 antibody, 7738 antibody, FLJ44613 antibody, Fodrin antibody, Fodrin alpha chain antibody, Fodrin, alpha antibody, NEAS antibody, Non erythrocytic spectrin alpha antibody, non-erythroid alpha chain antibody, SPECA antibody, Spectrin alpha chain antibody, Spectrin alpha chain brain antibody, Spectrin alpha non erythrocytic 1 antibody, Spectrin antibody, Spectrin non erythroid alpha chain antibody, Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) antibody, Spectrin, nonerythroid, alpha subunit antibody, Spna2 antibody, SPTA 2 antibody, SPTA2 antibody, SPTA2_HUMAN antibody, SPTAN 1 antibody, SPTAN1 antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

SPTAN1

NCBI Gene ID

6709

UniProt

Q13813

Host

Mouse

Reactivity

Bovine, Human, Mouse, and Rat

Immunogen

Recombinant contstruct containing the 7th, 8th, 9th repeats of human alpha II spectrin.

Immunogen Type

Human

Target

Alpha II Spectrin

Clonality

Monoclonal

Clone

3D7

Conjugation

Unconjugated

Applications

ELISA, WB, IHC, ICC

Concentration

1 mg/mL

Format

Protein G Purified

Form

Liquid

Buffer

PBS + 50% glycerol and 5 mm NaN3

Molecular Weight

240

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.