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Anti-Adenylate Cyclase III Antibody

Our Anti-Adenylate Cyclase III primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human, mouse, and rat Adenylate Cyclase III and is antigen affinity purified. It is great for use in WB, IHC, ICC.

Product Specifications

Background

Adenylate cyclase is the enzyme which produces the "second messenger" signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004; Louvi and Grove 2011) .

Synonyms

AC-III antibody, AC3 antibody, ADCY3 antibody, ADCY3_HUMAN antibody, adenylate cyclase 3 antibody, Adenylate cyclase antibody, Adenylate cyclase type 3 antibody, Adenylate cyclase type III antibody, Adenylyl cyclase 3 antibody, ATP pyrophosphate lyase antibody, ATP pyrophosphate-lyase 3 antibody, olfactive type antibody

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

ADCY3

NCBI Gene ID

64508

UniProt

P21932

Host

Rabbit

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat adenylate cyclase III, conjugated to keyhole limpet hemocyanin (KLH) .

Immunogen Type

Rat

Target

Adenylate Cyclase III

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB, IHC, ICC

Concentration

1 mg/ml

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 50% glycerol and 5 mm NaN3

Molecular Weight

160, 200

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

IHC Dilution

1:10,000

WB Dilution

1:2000

Specificity

Specific for endogenous levels of the ~160 kDa adenylate cyclase III protein.

Formulation

Affinity purified rabbit serum.

ICC Dilution

1:500-1:10,000

Quality Control

Western blots performed on each lot.

Isotype

IgG

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