Anti-Kappa Opioid Receptor Antibody

Our Kappa Opioid Receptor rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human Kappa Opioid Receptor and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors that activate intracellular signaling cascades and undergo endocytosis, recycling, or degradation upon stimulation. The (mu) m-, delta (d) and kappa (k) opioid receptors are GPCRs of the nervous system, which control pain, stress, and addictive behaviors. The kappa opioid receptor (KOR-1) plays a role in arousal and regulation of autonomic and neuroendocrine functions and is the receptor for dynorphins. KOR-1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Synonyms

OPRK1, Kappa-type opioid receptor, KOR-1

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

OPRK1

UniProt

P41145

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide corresponding to amino acids from the C-terminal region of the human KOR-1 protein

Immunogen Type

Human

Target

Kappa Opioid Receptor

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.