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Anti-Adrenergic Receptor Alpha 2c Antibody

Our Adrenergic Receptor Alpha 2c rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Adrenergic Receptor Alpha 2c and is antigen affinity purified. It is great for use in WB, IHC.

Product Specifications

Background

The alpha-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. There are 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha2C is required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons.

Synonyms

ADRA2C, Alpha-2C adrenoreceptor, Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, ADRA2L2, ADRA2RL2

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

ADRA2C

UniProt

P18825

Host

Rabbit

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide corresponding to amino acids from an internal region of the human adrenergic receptor alpha 2c protein

Immunogen Type

Human

Target

Adrenergic Receptor Alpha 2c

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

IHC Dilution

1:100-1:300

WB Dilution

1:500-1:1000

Specificity

Reacts with internal residues of the human Alpha 2c protein. Reacts with rat and mouse Alpha 2c.

Formulation

Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Isotype

IgG

Curated Selection

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