Anti-mGluR2/3 Antibody

Our mGluR2/3 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat mGluR2/3 and is antigen affinity purified. It is great for use in WB, IHC.

Product Specifications

Background

Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

Synonyms

Metabotropic glutamate receptor 2/3, GRM2, GRM3, Gprc1b

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

GRM2/3

UniProt

Q14416

Host

Rabbit

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide corresponding to amino acids from the C-terminal region of the human mGluR2/3 protein.

Immunogen Type

Human

Target

MGluR2/3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.