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Anti-PARK7 Antibody

Our PARK7 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse PARK7 and is antigen affinity purified. It is great for use in WB, IHC.

Product Specifications

Background

Four chromosomal loci (PARK2, PARK6, PARK7, and PARK9) associated with autosomal recessive, early onset parkinsonism are known. Positional cloning within the refined PARK7 critical region recently identified mutations in the DJ-1 gene in PARK7-linked families. Mutations in the PARK7/DJ-1 gene cause autosomal-recessive Parkinsons disease.

Synonyms

Parkinson disease (autosomal recessive, early onset) 7, DJ1 AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM/DEMENTIA COMPLEX 2, ONCOGENE DJ1, DJ-1, Parkinsonism-associated deglycase, zgc:103725

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

PARK7

UniProt

Q99497

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthetic peptide corresponding to amino acids from the C-terminal region of human PARK7.

Immunogen Type

Human

Target

PARK7

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

IHC Dilution

1:100-1:300

WB Dilution

1:500-1:1000

Specificity

Reacts with the C-terminal region of human and mouse PARK7 (DJ-1) . 82% sequence identity to rat PARK7.

Formulation

Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Isotype

IgG

Curated Selection

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