Anti-Ku80 Antibody

Our Ku80 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects hamster, human, mouse, and rat Ku80 and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

Telomere length maintenance, an activity essential for chromosome stability and genome integrity, is regulated by telomerase- and telomere-associated factors. The DNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates with mammalian telomeres and contributes to telomere maintenance. The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks. The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibited at chromosome ends

Synonyms

XRCC5, X-ray repair cross-complementing protein 5, ATP-dependent DNA helicase 2 subunit 2, Ku86, CTC box-binding factor 85 kDa subunit, Lupus Ku autoantigen protein p86, Thyroid-lupus autoantigen, TLAA, G22P2

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

XRCC5

UniProt

P13010

Host

Rabbit

Reactivity

Hamster, Human, Mouse, and Rat

Immunogen

Synthetic peptide corresponding to amino acids from an internal sequence of the human Ku80 protein

Immunogen Type

Human

Target

Ku80

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.