Anti-PRG3 Antibody
Our PRG3 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human PRG3 and is antigen affinity purified. It is great for use in WB.
Product Specifications
Background
The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway
Synonyms
Proteoglycan 3, Eosinophil major basic protein homolog, Prepro-major basic protein homolog, Prepro-MBPH
Other Statements
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Gene Name
PRG3
UniProt
Q9Y2Y8
Host
Rabbit
Reactivity
Human
Immunogen Type
Human
Target
PRG3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Format
Antigen Affinity Purified
Form
Liquid
Buffer
PBS + 0.02% NaN3
Shipping Conditions
Blue Ice
Storage Conditions
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
WB Dilution
1:500-1:1000
Specificity
Reacts with the 41 kDa human PRG3 protein. This sequence is 87% identical in mouse.
Formulation
Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
Quality Control
Western blots performed on each lot.
Isotype
IgG
Curated Selection
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