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Anti-CIDE3 Antibody

Our CIDE3 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human and mouse CIDE3 and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF) . DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45) . Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis.

Synonyms

CIDEC, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog, Lipid transferase CIDEC

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

CIDEC

UniProt

Q96AQ7

Host

Rabbit

Reactivity

Human and Mouse

Immunogen

Synthetic peptide corresponding to amino acids from the N-terminal region of human CIDE3 protein

Immunogen Type

Human

Target

CIDE3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Molecular Weight

27

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

WB Dilution

1:500-1:1000

Specificity

Reacts with the N-terminal region of human and mouse CIDE3 protein

Formulation

Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Isotype

IgG

Curated Selection

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